<html>
<body>
<div align="center"><font size=4><b>The UCSD Department of Cognitive
Science is pleased to announce a talk by<br><br>
</font><font size=6>Stefan Leutgeb Ph.D.<br><br>
</font><font size=4>Kavli Institute for Systems Neuroscience and <br>
Centre for the Biology of Memory<br><br>
Norwegian University for Science and Technology<br><br>
<br>
</font><font face="arial" size=4>Monday, February 4, 2008 at 12pm<br>
Cognitive Science Building, room 003<br><br>
</b></font><font size=6>"Map-based mechanisms for encoding
memories"<br><br>
</font></div>
<font size=4><b>The talk focuses on three main questions. First, is
spatial encoding the main organizing principle in CA3? Second, to what
extent does the spatial information originate upstream of hippocampus, in
the entorhinal cortex? Based on data addressing these first two
questions, I will then ask how memories can be stored in neuronal
networks that are tightly bound to a map-based coding scheme? In
experiments that combine single-unit recordings in hippocampal cell
populations with behavioral manipulations, I found that the use of
entirely different cell populations at two spatially distinct locations
results in retrieval dynamics that resemble distinct attractor states. In
contrast, mechanisms that allows for the gradual updating of previously
stored neuronal activity patterns are used when encoding multiple
memories at a recurring location.<br><br>
</font></b></body>
</html>